Immortality through uncontrolled cell division is a characteristic of cancer cells
The p53 gene is a tumour suppressor gene which prevents this
Mutations in this gene are present in more than 50% of cancers
Testing people for mutations in their p53 gene can indicate an increased risk in developing cancer
These tests raise intriguing ethical questions for both the individual tested and the family of an individual who chooses to be tested
In this experiment, students determine a pedigree for a family suspected to be carriers of mutations in their p53 genes
A DNA test indicates their likelihood of developing cancer
This Cancer Gene Detection Kit includes the reagents needed to produce up to 8 electrophoresis gels
Group Size: For 8 gels
Storage: Room Temperature stable, storage of Ready‐to Load QuickStrip™ DNA samples in the refrigerator is recommended
Time Required: Complete in 45 minutesThe kit includes:Full instructions
Ready‐to Load QuickStrip™ DNA samples
UltraSpec‐Agarose™
Electrophoresis Buffer (50x)
Practice Gel Loading Solution
FlashBlue™ DNA Stain
InstaStain® Blue Cards
Disposable pipettesAdditional required materials (not included with the kit):DNA Electrophoresis Tank, with accessories including casting trays, micropipettes & special power supply (B8R03273)
